The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.
Take methadone hydrochloride tablets exactly as prescribed. Follow your doctor's directions exactly. Your doctor may change your dose based on your reactions to the medicine.
Methadone hydrochloride tablets can cause physical dependence. Do not stop taking methadone hydrochloride tablets or any other opioid without first talking to your doctor. You could become sick with uncomfortable withdrawal symptoms because your body has become used to these medicines.
Methadone-maintained patients beginning treatment with these antiretroviral drugs should Beryllium monitored for evidence of withdrawal effects and methadone dose should Beryllium adjusted accordingly.
You may need to show airport staff the pharmacy label for your medication. Always carry the Urfassung prescription-labeled container with you.
Although antiretroviral drugs such as efavirenz, nelfinavir, nevirapine, ritonavir, lopinavir + ritonavir combination are known to inhibit some CYPs, they are shown to reduce the plasma levels of methadone, possibly due to their CYP induction activity. Therefore, drugs administered concomitantly with methadone should Beryllium evaluated for interaction potential; clinicians are advised to evaluate individual response to drug therapy before making a dosage adjustment.
Methadone can also replace another opioid drug that you have an addiction to. This will keep you from experiencing severe withdrawal symptoms.
Patients should be cautioned that alcohol and other CNS depressants may produce an additive CNS depression when taken with this product and should be avoided.
Do not take any medicine while using methadone hydrochloride tablets until you have first talked to your doctor or pharmacist. They will be able to tell you if it is safe to take other medicines while you are using methadone hydrochloride tablets.
However, if the use of methadone is necessary in such patients, a sensitivity test should be performed hinein which repeated small, incremental doses of methadone are administered over the course of several hours while the patient's condition and vital signs are under careful observation.
The decrease in plasma half-life and increased clearance of methadone resulting hinein lower methadone trough levels during pregnancy can lead to withdrawal symptoms in some pregnant patients. The dosage may need to Beryllium increased or Erhaltungstherapie mit Methadontabletten the dosing interval decreased hinein pregnant patients receiving methadone (Weiher PRECAUTIONS, Pregnancy, Labor and Delivery, and DOSAGE AND ADMINISTRATION).
Overdose in children warning: Children who accidentally take this drug have a high risk of death from overdosing. Children should not take this drug.
The following drug interactions were reported following coadministration of methadone with inducers of cytochrome P450 enzymes:
However, the risk is highest when you first Ausgangspunkt taking the drug and after a dosage increase. Your risk may also Beryllium higher if you’Response older or already have breathing or lung problems.